KRT20, keratin 20, 54474

N. diseases: 559; N. variants: 1
Disease: Trisomy 12 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0432408
Disease: Trisomy 12
Trisomy 12 		0.050 AlteredExpression phenotype BEFREE Expression of CD20 was dimmer and that of CD43 brighter in trisomy 12 MBL than in cases with trisomy 12 and 3 Moreau criteria. 28187524 2018
CUI: C0432408
Disease: Trisomy 12
Trisomy 12 		0.050 AlteredExpression phenotype BEFREE In summary, our results confirm a high CD23a/CD23b ratio of the CLL cells and demonstrate that in a subset of CLL cases, low CD23 expression together with high CD20 and CD38 expressions may serve as a surrogate for trisomy 12. 26119874 2017
CUI: C0432408
Disease: Trisomy 12
Trisomy 12 		0.050 AlteredExpression phenotype BEFREE Patients with trisomy 12 CLL showed strong leukemic cell CD20 expression and had a high rate of response to rituximab-based therapy. 18324964 2008
CUI: C0432408
Disease: Trisomy 12
Trisomy 12 		0.050 AlteredExpression phenotype BEFREE Rapidly progressive and fatal course of the disease was consistent with known bad prognostic significance of CD20 bright expression and trisomy 12. 10382945 1999
CUI: C0432408
Disease: Trisomy 12
Trisomy 12 		0.050 AlteredExpression phenotype BEFREE Trisomy 12 cases demonstrated a significant higher expression of CD11a (P<0.0001) and CD20 (P<0.0006) when compared to cases with the equivalent morphology and immunophenotype, but without the chromosomal abnormality. 9576197 1998