ATR, ATR serine/threonine kinase, 545

N. diseases: 321; N. variants: 38
Disease: ovarian neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.320 Biomarker disease BEFREE The recent approval of three different PARP inhibitors for the treatment of ovarian cancer provides the impetus for further developing targeted inhibitors of many of the kinases involved in the DDR, including inhibitors of ATR, ATM, CHEK1, CHEK2, DNAPK and WEE1. 28984489 2017
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.320 GeneticVariation disease BEFREE The present study does not support a major role for ATR mutations in hereditary susceptibility to breast and ovarian cancer. 15987455 2005
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.320 GenomicAlterations disease CGI
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.320 CausalMutation disease CGI