Multivariate analyses demonstrated that an intraoperative reduction of SBP more than 50% was associated with a more than doubled risk of AKI, adjusted odds ratio 2.27; 95% CI, 1.20 to 4.30, P = 0.013.
Higher contrast volume to creatinine clearance ratio (2.40±1.44 vs. 2.08±1.15; p=0.01), lower post-procedural mean arterial pressure (MAP) (94.3±17.7 vs. 99.6±18.5 mmHg; p=0.003) and a more frequent post-procedural systolic pressure drop (∆SBP >50 mmHg) (23.9% vs. 14.3%, p=0.01) were observed in the AKI group of patients.
However attention should be taken on diastolic BP if lower than 70 mmHg because of an increasing risk of ischemic heart event and on renal function since acute renal failure is more frequently reported at these low targets.In diabetic patients, SBP target should be less than 140 mmHg according to ACCORD trial.