CRCT1, cysteine rich C-terminal 1, 54544

N. diseases: 8; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017574
Disease: Gingivitis
Gingivitis
0.010 GeneticVariation disease BEFREE A panel of four salivary exRNAs [SPRR1A, lnc-TET3-2:1, FAM25A, CRCT1] can detect gingivitis with a clinical performance of 0.91 area under the curve, with 71% sensitivity and 100% specificity. 29779262 2018
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.010 Biomarker group BEFREE Cysteine-rich C-terminal 1 (CRCT1) is encoded by the epidermal differentiation complex (EDC), a gene cluster that was recently linked to esophageal cancer. 26718216 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE Our results suggest that CRCT1 functions as a tumor suppressor gene in ESCC and is regulated by miR-520 g, providing potential therapeutic targets for the treatment of ESCC. 26718216 2016
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.010 Biomarker disease BEFREE Cysteine-rich C-terminal 1 (CRCT1) is encoded by the epidermal differentiation complex (EDC), a gene cluster that was recently linked to esophageal cancer. 26718216 2016
Squamous cell carcinoma of esophagus
0.010 Biomarker disease BEFREE Our results suggest that CRCT1 functions as a tumor suppressor gene in ESCC and is regulated by miR-520 g, providing potential therapeutic targets for the treatment of ESCC. 26718216 2016
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.010 Biomarker disease BEFREE Cysteine-rich C-terminal 1 (CRCT1) is encoded by the epidermal differentiation complex (EDC), a gene cluster that was recently linked to esophageal cancer. 26718216 2016
Secondary malignant neoplasm of lymph node
0.010 AlteredExpression disease BEFREE In the present study, we show that CRCT1 is downregulated in ESCC in association with TNM stage and lymph node metastasis. 26718216 2016
CUI: C1832097
Disease: EPIDERMAL DIFFERENTIATION COMPLEX
EPIDERMAL DIFFERENTIATION COMPLEX
0.010 Biomarker disease BEFREE Cysteine-rich C-terminal 1 (CRCT1) is encoded by the epidermal differentiation complex (EDC), a gene cluster that was recently linked to esophageal cancer. 26718216 2016