POU4F1, POU class 4 homeobox 1, 5457

N. diseases: 54; N. variants: 0
Disease: cervical cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.320 Biomarker disease CTD_human We observed that BRN3A is independent of the regulative activity of HIPK2 and undergoes positive autoregulation in cervical cancer cells. 21928122 2011
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.320 Biomarker disease BEFREE These results indicate that Brn-3a could play an important role in the near future in improving cervical cancer screening. 12911730 2004
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.320 AlteredExpression disease BEFREE The elevated levels of Brn-3a in the CIN3 patient samples, together with the activating effect of Brn-3a on HPV-16 and -18 oncogene expression, suggest that induction of this factor is involved in activating HPV-16 and -18 oncogene expression in the cervix, and hence in the production of cervical cancers induced by HPV. 9541499 1998