Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Although ample evidence exists for a positive correlation between HIFs and tumor formation, metastasis and poor prognosis, the function of the PHD2 in carcinogenesis is less well understood. 30817904 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Proline hydroxylase 2 (PHD2) is involved in tumorigenesis. 31819628 2019
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE The role of prolyl hydroxylase domain protein 2 (PHD2) in carcinogenesis has been studied in a variety of cancer types. 25546659 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Although ample evidence exists for a positive correlation between hypoxia-inducible factors (HIFs) and tumor formation, metastasis and bad prognosis, the function of the HIF-α protein stability regulating prolyl-4-hydroxylase domain enzyme PHD2 in carcinogenesis is less well understood. 20856199 2011
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.050 Biomarker phenotype BEFREE Elevated PHD1 concomitant with decreased PHD2 are causatively related to Rpb1 hydroxylation and oncogenesis in human RCC tumors with WT VHL gene. 20978146 2010