Disease: Colonic Polyps ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009376
Disease: Colonic Polyps
Colonic Polyps 		0.050 GeneticVariation phenotype BEFREE This is the first PPARG germline mutation associated with dyslipidemia and colonic polyp formation that can progress to full-blown adenocarcinoma. 20123124 2010
CUI: C0009376
Disease: Colonic Polyps
Colonic Polyps 		0.050 Biomarker phenotype BEFREE PPARgamma hetero-deficiency promoted the induction of ACF, but had no effect on the incidence of colonic polyps. 18391483 2008
CUI: C0009376
Disease: Colonic Polyps
Colonic Polyps 		0.050 AlteredExpression phenotype BEFREE In this study we evaluated the expression of PPARgamma in the biopsy samples of the polyps and outside polyps colonic mucosa from seven patients with active, untreated acromegaly, 11 with cured disease, and 15 controls. 12915690 2003
CUI: C0009376
Disease: Colonic Polyps
Colonic Polyps 		0.050 GeneticVariation phenotype BEFREE In this study the expression and mutations of the PPARgamma gene in the colonic polyps and mucosa outside polyps were investigated in 10 acromegalic and 17 non-acromegalic patients. 15008240 2003
CUI: C0009376
Disease: Colonic Polyps
Colonic Polyps 		0.050 AlteredExpression phenotype BEFREE In conclusion, patients with active Acro have a reduced expression of PPARgamma in the colonic mucosa, which appears be related to the increased serum IGF-I levels and might lead to an increased prevalence of colonic polyps. 11994396 2002