PPID, peptidylprolyl isomerase D, 5481

N. diseases: 72; N. variants: 2
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.020 Biomarker disease BEFREE Neutrophil depletion in wildtype mice conferred protection from ischemic stroke similarly to mice with CypD-deficient platelets. 31800959 2020
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.020 Biomarker disease BEFREE Our study firstly identifies ERK-CypD axis is one of the cornerstones of the cell death pathways following ischemic stroke, and confirms GA is a novel inhibitor of MPTP, which inhibits apoptosis depending on regulating the ERK-CypD axis. 28428752 2017