CASZ1, castor zinc finger 1, 54897

N. diseases: 132; N. variants: 15
Disease: Disorder of vein ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235522
Disease: Disorder of vein
Disorder of vein 		0.010 GeneticVariation group BEFREE This study demonstrates that the CASZ1 gene associated C-allele of rs11121615 has a significant, reproducible, association with CVD (CEAP C ≥ 2 meta-odds ratio 1.31, 95% CI 1.27-1.34, P = 1 × 10<sup>-98</sup>, PHet = 0.25), but not with non-varicose vein (CEAP C1, telangiectasia or reticular veins) forms of venous disease. 31570750 2019