Disease: Impaired insulin secretion ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948379
Disease: Impaired insulin secretion
Impaired insulin secretion 		0.040 Biomarker disease BEFREE The CDKAL1 gene is associated with impaired insulin secretion and glucose-related traits: the Cardiometabolic Risk in Chinese (CRC) study. 26119585 2015
CUI: C0948379
Disease: Impaired insulin secretion
Impaired insulin secretion 		0.040 GeneticVariation disease BEFREE Cdkal1 gene deletion is accompanied by modestly impaired insulin secretion and longitudinal fluctuations in insulin sensitivity during high-fat feeding in mice. 23173044 2012
CUI: C0948379
Disease: Impaired insulin secretion
Impaired insulin secretion 		0.040 GeneticVariation disease BEFREE These results suggest that the interaction between the CDKAL1 polymorphism and dietary energy intake influences the dysglycemic phenotype leading to MetS, possibly through impaired insulin secretion. 20847106 2010
CUI: C0948379
Disease: Impaired insulin secretion
Impaired insulin secretion 		0.040 GeneticVariation disease BEFREE rs7754840 of CDKAL1 was associated with markers of impaired insulin secretion in two independent studies. 18285412 2008