Disease: Colonic Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.060 AlteredExpression group BEFREE Human cytochome P450 2W1 (CYP2W1) enzyme is expressed in fetal colon and in colon tumors. 27598485 2016
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.060 Biomarker group BEFREE Indolines constitute high affinity exogenous compounds and specific chloromethylindolines have been shown to be activated by CYP2W1 into cytotoxic products in vitro and also in vivo, inhibiting the growth of human colon tumors in a mouse xenograft model. 27257736 2016
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.060 Biomarker group BEFREE Cytochrome P450 2W1 (CYP2W1) is a colon tumor-specific enzyme, suggested as a potential target for cancer therapy. 26787547 2016
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.060 AlteredExpression group BEFREE Developmental regulation and induction of cytochrome P450 2W1, an enzyme expressed in colon tumors. 25844926 2015
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.060 AlteredExpression group BEFREE The expression of CYP2W1 is colon tumor-specific and is associated with methylation status of the CYP2W1 gene, suggesting a potential causal link between the gene hypomethylation and its enhanced expression. 17979506 2007
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.060 AlteredExpression group BEFREE Western blotting also revealed high expression of CYP2W1 in some human colon tumors. 16426568 2006