Disease: Carcinosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007140
Disease: Carcinosarcoma
Carcinosarcoma 		0.020 GeneticVariation disease BEFREE Somatic missense mutations in the Ser/Thr protein phosphatase 2A (PP2A) Aα scaffold subunit gene PPP2R1A are among the few genomic alterations that occur frequently in serous endometrial carcinoma (EC) and carcinosarcoma, two clinically aggressive subtypes of uterine cancer with few therapeutic options. 27485451 2016
CUI: C0007140
Disease: Carcinosarcoma
Carcinosarcoma 		0.020 GeneticVariation disease BEFREE The molecular profile of carcinosarcomas suggests two distinct mutation profiles for these tumours: endometrioid-type (PTEN, PIK3CA, ARID1A, KRAS mutations) and serous-type (TP53 and PPP2R1A mutations). 22653804 2012