NADSYN1, NAD synthetase 1, 55191

N. diseases: 14; N. variants: 11
Disease: Vitamin D Deficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.140 GeneticVariation disease BEFREE Variants of NADSYN1/DHCR7 were significantly associated with 25(OH)D concentrations among pregnant women without vitamin D supplements. 29153269 2018
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.140 GeneticVariation disease BEFREE To date, at least 3 candidate genes, vitamin D binding protein (VDBP) gene (GC), 25-hydroxylase (CYP2R1), and 7-dehydrocholesterol reductase/NAD synthetase 1 (DHCR7/NADSYN1), have been associated with serum 25-hydroxyvitamin D (25[OH]D) levels, but their influences on the prevalence of vitamin D deficiency in relation to other known risk factors have not been clearly defined. 25370324 2015
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.140 GeneticVariation disease BEFREE Polymorphisms in CYP2R1-rs10766197 and DHCR7/NADSYN1-rs12785878 are associated with vitamin D deficiency in Uygur and Kazak ethnic populations. 26149120 2015
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.140 GeneticVariation disease BEFREE Although this is a small study, our findings suggest that VDR, NADSYN1, and GC polymorphisms may be linked to the manifestation of vitamin D deficiency in Japanese children. 22785457 2012
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.140 GeneticVariation disease GWASDB Common genetic determinants of vitamin D insufficiency: a genome-wide association study. 20541252 2010
CUI: C0042870
Disease: Vitamin D Deficiency
Vitamin D Deficiency 		0.140 GeneticVariation disease GWASCAT Common genetic determinants of vitamin D insufficiency: a genome-wide association study. 20541252 2010