Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.040 Biomarker disease BEFREE G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. 28351524 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.040 GeneticVariation disease BEFREE Aberrant expression, mutations and somatic alterations of the PP2A scaffold and regulatory subunits have been observed in various human malignancies, including lung, breast, skin and colon cancer, highlighting its role as a 'tumor suppressor'. 23454242 2013
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.040 Biomarker disease BEFREE Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer. 22581840 2012
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.040 Biomarker disease BEFREE RT-PCR method was employed to examine the constitutive mRNA expression of Stat6 negative regulators SOCS-1 and SHP-1, and positive regulator PP2A in colon cancer cell lines HT-29 and Caco-2. 18536936 2009