Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE In addition, we demonstrated the formation of the SETBP1-SET-PP2A heterotrimeric complex in CRC cells. 29796729 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 AlteredExpression disease BEFREE LB-100 is a novel PP2A inhibitor.Its activity in human colorectal cancer (CRC) cells was tested. 29221169 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia. 28199842 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE Here, we report the role of PP2A inhibitor PME-1 in CRC. 26377365 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE These results suggest that PP2A activity is commonly decreased in colorectal cancer cells, and that the use of PP2A activators, such as FTY720, might represent a potential novel therapeutic strategy in colorectal cancer. 24448818 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 PosttranslationalModification disease BEFREE Here, we show that PPP2R2B, encoding the B55β regulatory subunit of the PP2A complex, is epigenetically inactivated by DNA hypermethylation in colorectal cancer. 21075311 2010
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.070 Biomarker disease BEFREE PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers. 14767517 2004