Disease: Congestive heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.040 AlteredExpression disease BEFREE Thus, PR65A phosphorylation is an in vivo mechanism for regulation of the PP2A signaling complex and increased PP2A activity in heart failure. 24465463 2014
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.040 AlteredExpression disease BEFREE The decreased PP2A activity observed in HF was accompanied by enhanced Ca(2+)/calmodulin-dependent protein kinase (CaMKII)-mediated phosphorylation of RyR2 at sites Ser-2814 and Ser-2030 and increased frequency of diastolic Ca(2+) waves and afterdepolarizations in HF myocytes compared with controls. 22163007 2011
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.040 AlteredExpression disease BEFREE Increased levels of PP2A that colocalize with Cx43 can underlie enhanced levels of Cx43-NP in HF. 15576650 2005
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.040 AlteredExpression disease BEFREE PP2A expression demonstrated a significant upregulation in skeletal muscle biopsies from patients with CHF as compared to healthy controls (9.7 +/- 1.9 vs. 4.2 +/- 0.7 arbitrary units; p<0.05). 14567976 2004