Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.030 GeneticVariation disease BEFREE Novel B55α-PP2A mutations in AML promote AKT T308 phosphorylation and sensitivity to AKT inhibitor-induced growth arrest. 27531894 2016
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.030 AlteredExpression disease BEFREE We recently discovered that the protein phosphatase 2A (PP2A) B55α subunit (PPP2R2A) is under-expressed in primary blast cells and is unfavorable for remission duration in AML patients. 24858343 2014
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.030 Biomarker disease BEFREE Reactivating PP2A by FTY720 as a novel therapy for AML with C-KIT tyrosine kinase domain mutation. 22109829 2012