|
Schizophrenia
|
0.630 |
Biomarker
|
disease |
BEFREE |
Moreover, mice with conditional knockout of calcineurin B (CNB-KO) exhibit behavioral abnormalities suggestive of schizophrenia.
|
29427598 |
2018 |
|
Schizophrenia
|
0.630 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
|
Schizophrenia
|
0.630 |
AlteredExpression
|
disease |
LHGDN |
Calcineurin A gamma and B gene expressions in the whole blood in Japanese patients with schizophrenia.
|
18343007 |
2008 |
|
Schizophrenia
|
0.630 |
Biomarker
|
disease |
PSYGENET |
Forebrain-specific CNB knockout mice display a spectrum of behavioral abnormalities related to altered behaviors observed in schizophrenia patients.
|
12851458 |
2003 |
|
Schizophrenia
|
0.630 |
Biomarker
|
disease |
BEFREE |
Forebrain-specific CNB knockout mice display a spectrum of behavioral abnormalities related to altered behaviors observed in schizophrenia patients.
|
12851458 |
2003 |
|
Schizophrenia
|
0.630 |
Biomarker
|
disease |
MGD |
|
|
|
|
Myocardial Ischemia
|
0.500 |
Biomarker
|
disease |
CTD_human |
Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study.
|
16214533 |
2005 |
|
Myocardial Ischemia
|
0.500 |
Biomarker
|
disease |
RGD |
Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study.
|
16214533 |
2005 |
|
Left Ventricular Hypertrophy
|
0.320 |
GeneticVariation
|
disease |
LHGDN |
Thus, CNB gene 5I/5D polymorphism is associated with the risk of left ventricular hypertrophy and physical performance of athletes.
|
18825932 |
2008 |
|
Left Ventricular Hypertrophy
|
0.320 |
Biomarker
|
disease |
CTD_human |
Angiotensin-converting enzyme inhibitor suppresses activation of calcineurin in renovascular hypertensive rats.
|
18344631 |
2007 |
|
Left Ventricular Hypertrophy
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We identified a novel 5-base pair (bp) insertion/deletion (5I/5D) polymorphism within the CnB promoter region and investigated its association with left ventricular hypertrophy (LVH) in 368 severe hypertensive participants (53% African Americans) in the Hypertension Genetic Epidemiology Network study.
|
16209992 |
2005 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
|
29326435 |
2019 |
|
Potassium measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.
|
31409800 |
2019 |
|
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
|
21194676 |
2011 |
|
Cornea plana
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Cornea plana congenita is believed to occur in a mild autosomal dominant (CNA1) and a more severe autosomal recessive (CNA2) form.
|
8929947 |
1996 |
|
Cornea plana
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Cornea plana congenita occurs in a mild autosomal dominant (CNA1) and a more severe autosomal recessive (CNA2) form.
|
8723718 |
1996 |
|
Cornea plana
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Linkage disequilibrium mapping of the cornea plana congenita gene CNA2.
|
8825624 |
1995 |
|
Cornea plana
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
We report the mapping of the locus for autosomal recessive cornea plana congenita (CNA2; MIM 217300) by linkage analysis to the approximately 10-cM interval between markers D12S82 and D12S327.
|
7601455 |
1995 |
|
Alzheimer's Disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
Since aberrant activation of microglia is involved in the pathogenesis of Alzheimer's disease, the present study was undertaken to investigate the effect of CNB-001 on microglia-mediated inflammatory responses.
|
29221948 |
2018 |
|
Alzheimer's Disease
|
0.030 |
Biomarker
|
disease |
BEFREE |
We observe that central genes, namely PSEN1, APP, NDUFB2, NDUFA1, UQCR10, PPP3R1 and a few more, play significant roles in the AD.
|
30466046 |
2018 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
The diagnostic yield for malignancy was 30/32 (93.7%) for FNA and 23/32 (71.8%) for CNB (P = .043).
|
29227044 |
2018 |
|
Malignant Neoplasms
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Patients' age (odds ratio [OR] = 3.63, P = 0.008), lesion consistency (OR = 5.96, P = 0.001), BI-RADS category (OR = 17.52, P < 0.001), and CNB result (OR = 3.6, P = 0.008) were associated with a higher risk of malignancy underestimation and selected as risk factors in the score definition.
|
30216597 |
2018 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
The diagnostic yield for malignancy was 30/32 (93.7%) for FNA and 23/32 (71.8%) for CNB (P = .043).
|
29227044 |
2018 |