PARL, presenilin associated rhomboid like, 55486

N. diseases: 20; N. variants: 8
Disease: Leprosy, Multibacillary ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1562585
Disease: Leprosy, Multibacillary
Leprosy, Multibacillary 		0.010 GeneticVariation disease BEFREE We found that PARL SNP rs12631031 conferred a risk to leprosy (P<sub>adjusted</sub> = 0.019) and multibacillary leprosy (MB, P<sub>adjusted</sub> = 0.020) at the allelic level. rs12631031 and rs7653061 in PARL were associated with leprosy and MB (dominant model, P<sub>adjusted</sub> < 0.05) at the genotypic level. 27876828 2016