PREP, prolyl endopeptidase, 5550

N. diseases: 105; N. variants: 1
Disease: Mood swings ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085633
Disease: Mood swings
Mood swings 		0.010 Biomarker disease BEFREE This unexpected result suggests a model that could explain the dual action of VPA in stabilizing mood: we propose that euthymic mood is dependent on stable PIns signaling and that VPA may limit mood swings to mania by decreasing PIns signaling, and that it may limit mood swings to depression by inhibiting PO and thus increasing PIns signaling. 15911340 2005