PREP, prolyl endopeptidase, 5550

N. diseases: 105; N. variants: 1
Disease: Euthymic mood ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233475
Disease: Euthymic mood
Euthymic mood 		0.010 Biomarker disease BEFREE This unexpected result suggests a model that could explain the dual action of VPA in stabilizing mood: we propose that euthymic mood is dependent on stable PIns signaling and that VPA may limit mood swings to mania by decreasing PIns signaling, and that it may limit mood swings to depression by inhibiting PO and thus increasing PIns signaling. 15911340 2005