Disease: Childhood Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE We have previously demonstrated that TROY (TNFRSF19) plays an important role in glioblastoma cell invasion and therapeutic resistance. 30219706 2018
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 AlteredExpression disease BEFREE TROY expression significantly increases the capacity of EGF to stimulate glioblastoma cell invasion, whereas depletion of TROY expression blocks EGF stimulation of glioblastoma cell invasion. 29117939 2018
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 Biomarker disease BEFREE These findings position aberrant expression and/or signaling by TROY as a contributor to the dispersion of glioblastoma cells and therapeutic resistance. 23699535 2013
CUI: C0280474
Disease: Childhood Glioblastoma
Childhood Glioblastoma 		0.040 AlteredExpression disease BEFREE TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling. 20881009 2010