SOX6, SRY-box transcription factor 6, 55553

N. diseases: 105; N. variants: 46
Disease: beta^+^ Thalassemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3841475
Disease: beta^+^ Thalassemia
beta^+^ Thalassemia 		0.020 Biomarker disease BEFREE Disruption of SOX6 gene using CRISPR/Cas9 technology for gamma-globin reactivation: An approach towards gene therapy of β-thalassemia. 30010219 2018
CUI: C3841475
Disease: beta^+^ Thalassemia
beta^+^ Thalassemia 		0.020 AlteredExpression disease BEFREE The ZFN strategy applied here to induce indel on SOX6 gene in adult erythroid progenitors may provide a method to activate fetal hemoglobin expression in individuals with β-thalassemia. 28941328 2018