Disease: Ureteral obstruction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.030 Biomarker phenotype BEFREE In animal model of UUO, febuxostat reduced the UUO-induced ER stress, which was abolished by pretreatment with SIRT1 inhibitor (sirtinol) and AMPK inhibitor (compound C). 31677062 2020
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.030 Biomarker phenotype BEFREE Mice with global or fibroblast-specific knockout of AMPKα1 exhibited fewer myofibroblasts, developed less fibrosis, and produced less extracellular matrix protein in the kidneys following unilateral ureteral obstruction or ischemia-reperfusion injury. 28739141 2018
CUI: C0041956
Disease: Ureteral obstruction
Ureteral obstruction 		0.030 Biomarker phenotype BEFREE NaHS-treatment may exert a protective effect on mouse kidney against UUO by suppressing the ROS-AMPK pathway. 30257249 2018