Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 Biomarker disease BEFREE In this study, AMPKα2 knockout mice and the liver metastasis model of colon cancer cells were used to address the role of AMPKα isoforms in tumour inflammation. 30636376 2019
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 Biomarker disease BEFREE Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. 29535833 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 AlteredExpression disease BEFREE Here we show that individual AMPK subunit expression and requirement for survival varies across colon cancer cell lines. 29491475 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 Biomarker disease BEFREE Mechanistically, co-culture of adipocytes or treating cells with fatty acids induced autophagy in colon cancer cells as a result of AMPK activation. 28151470 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 Biomarker disease BEFREE Torilis japonica extract-generated intracellular ROS induces apoptosis by reducing the mitochondrial membrane potential via regulation of the AMPK-p38 MAPK signaling pathway in HCT116 colon cancer. 27314881 2016
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 Biomarker disease BEFREE Therefore, AMPK α2 might represent an important therapeutic target for colon cancer metastasis-induced liver injury. 24515110 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.070 AlteredExpression disease BEFREE The SNF1/AMPK-related protein kinase Hunk is overexpressed in aggressive subsets of human breast, ovarian, and colon cancers. 21393859 2011