MFN1, mitofusin 1, 55669

N. diseases: 45; N. variants: 1
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.020 PosttranslationalModification disease BEFREE Mfn1 phosphorylation results in partial loss of its GTPase activity and in a buildup of fragmented and dysfunctional mitochondria in heart failure. 30659190 2019
CUI: C0018801
Disease: Heart failure
Heart failure 		0.020 AlteredExpression disease BEFREE The mRNA upregulation of Mitofusin 1 and 2 provides first insight into the complex changes of mitochondrial dynamics in cardiomyocytes of patients with reversible heart failure due to TCM. 30873819 2019