ENAH, ENAH actin regulator, 55740

N. diseases: 47; N. variants: 0
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE Compared with MENA, higher levels of the prometastatic MENA(INV) isoform associate with α5, which enables 3-D haptotaxis of tumor cells toward the high FN concentrations typically present in perivascular space and in the periphery of breast tumor tissue. 26811325 2016
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 Biomarker group BEFREE Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors. 23129656 2012
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group LHGDN The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors. 16533770 2006