Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 PosttranslationalModification disease BEFREE Neither APC mutation status nor CHFR methylation status correlated with efficacy in the CIMP-high CRC cohort. 29069279 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 Biomarker disease BEFREE Our data suggested that CHFR could be a potential drug target for development of demethylation treatment for patients with CRC. 29179506 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 PosttranslationalModification disease BEFREE CHFR promoter CpG island methylation, which is associated with MSI, also occurs frequently in MSS CRCs and is a promising prognostic marker in stage II, MSS, BRAF WT CRCs. 24928946 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 Biomarker disease BEFREE Cell lines that were MSI-H/CHFR-methylated, MSS/CHFR-methylated and MSS/CHFR-unmethylated were assessed for in vivo sensitivity of CRC cell line xenografts to docetaxel and/or gemcitabine. 23873170 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 GeneticVariation disease BEFREE These results reveal for the first time that polymorphisms in the CHFR gene are associated with colorectal cancer susceptibility. 18079053 2008
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.060 PosttranslationalModification disease BEFREE These findings suggest that CHFR might act as a tumor suppressor in at least some colorectal cancers and that CHFR methylation might, therefore, be a particular phenomenon of early colorectal cancer. 17201143 2007