Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.330 Biomarker disease BEFREE Our data indicate that RNA interference targeting CHFR can sensitize endometrial cancer cells to taxol and CHFR may be a promising molecular target to enhance the therapeutic effect of taxol for endometrial cancer. 22469813 2012
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.330 AlteredExpression disease BEFREE Here, we studied the correlations between the checkpoint with forkhead-associated and ring finger (CHFR) gene expression and responses to paclitaxel in endometrial cancer cells. 21792009 2011
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.330 GeneticVariation disease BEFREE For example, aberrant hypermethylation of the CHFR gene is correlated with cellular sensitivity to microtubule inhibitors, and this may be useful in treatment of type I endometrial cancer. 19787208 2009
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.330 Biomarker disease CTD_human Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer. 17143476 2007