Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 Biomarker disease BEFREE Silencing of CHFR Sensitizes Gastric Carcinoma to PARP Inhibitor Treatment. 31812083 2020
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 PosttranslationalModification disease BEFREE CHFR is frequently methylated in human gastric cancer, and CHFR methylation may serve as a docetaxel-sensitive marker. 24748501 2015
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 PosttranslationalModification disease BEFREE DAPK and CHFR promoter hypermethylation may be an important help in evaluating the differentiation grade and lymph node status of gastric cancer. 21302620 2011
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 Biomarker disease BEFREE Aberrant promoter methylation of Runx3 and CHFR genes may be involved in the carcinogenesis and development of GC and may provide useful clues for the prediction of the malignant behaviors of GC. 20300977 2011
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 PosttranslationalModification disease BEFREE Aberrant methylation of the CHFR gene is a frequent event in the carcinogenesis of gastric cancer. 20109344 2010
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 PosttranslationalModification disease BEFREE Aberrant methylation of the CHFR gene may be involved in the carcinogenesis and development of GC, and is the predominant cause of down-regulation or loss of CHFR mRNA or protein expression. 18763281 2008
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 PosttranslationalModification disease BEFREE Thus, Chfr promoter hypermethylation is mostly cancer specific and frequently leads to chromosome instability in gastric cancer. 15138487 2004
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.080 AlteredExpression disease BEFREE By affecting mitotic checkpoint function, CHFR inactivation likely plays a key role in tumorigenesis in gastric cancer. 14695171 2003