PRKCA, protein kinase C alpha, 5578

N. diseases: 368; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Biomarker phenotype CTD_human The expression of PKCα, which is regulated by Ca(2+)and known to stimulate cardiac hypertrophy, was significantly increased in the vehicle group, and PC, EP or PC + EP effectively decreased PKCα activation. 21565836 2011