PRKD1, protein kinase D1, 5587

N. diseases: 171; N. variants: 19
Disease: Triple-Negative Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722518
Disease: Triple-Negative Breast Carcinoma
Triple-Negative Breast Carcinoma 		0.020 AlteredExpression disease BEFREE The effects of inhibiting PRKD activity with CRT0066101 on TNBC cell proliferation, cell cycle, apoptosis, and tumor growth were studied by Cell Counting Kit8 assay, cell cycle assay, propidium iodide/annexin-V assay, and a xenograft mouse model, respectively. 30845378 2019
CUI: C4722518
Disease: Triple-Negative Breast Carcinoma
Triple-Negative Breast Carcinoma 		0.020 AlteredExpression disease BEFREE We identified novel PKD1 inhibitors and assessed their antitumor activity <i>in vitro</i> in TNBC cell lines and <i>in vivo</i> in a TNBC patient-derived xenograft (PDX) model. 29796183 2018