MAPK6, mitogen-activated protein kinase 6, 5597

N. diseases: 40; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE ERK3 is a newfound potential prognostic predictor and a tumor suppressor in ICC. 28241849 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 AlteredExpression group BEFREE Mechanistically, BMI1 upregulates ERK3 expression by suppressing the tumor suppressive microRNA (miRNA) let-7i, which directly targets ERK3 mRNA. 28079973 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Importantly, knockdown of ERK3 or SRC-3 inhibited the ability of lung cancer cells to invade and form tumors in the lung in a xenograft mouse model. 22505454 2012