MAPK7, mitogen-activated protein kinase 7, 5598

N. diseases: 127; N. variants: 6
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.040 AlteredExpression disease BEFREE Increased ERK5 expression was correlated with poor overall survival in colon cancer patients. 27144434 2016
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.040 AlteredExpression disease BEFREE Expression of MEK5 and ERK5 was evaluated in 323 human colon cancer samples. 25855966 2015
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.040 Biomarker disease BEFREE On the contrary, an extracellular signal-regulated protein kinase 5 (ERK5), which was determined to be a target of miR-143 in colon cancer DLD-1 cells, was time-dependently down-regulated at the translational level after the treatment. 19464056 2009
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.040 Biomarker disease BEFREE The transfection of each precursor miRNA into the cells demonstrated a significant growth inhibition in human colon cancer DLD-1 and SW480 cells, and ERK5 was determined to be the target gene of miRNA 143. 16969504 2006