MAPK8, mitogen-activated protein kinase 8, 5599

N. diseases: 520; N. variants: 4
Disease: Small cell carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.030 AlteredExpression disease BEFREE Doxorubicin induces expression of multidrug resistance-associated protein 1 in human small cell lung cancer cell lines by the c-jun N-terminal kinase pathway. 15880572 2005
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.030 Biomarker disease BEFREE Regulation of platinum-compound cytotoxicity by the c-Jun N-terminal kinase and c-Jun signaling pathway in small-cell lung cancer cells. 12181446 2002
CUI: C0149925
Disease: Small cell carcinoma of lung
Small cell carcinoma of lung 		0.030 Biomarker disease BEFREE The findings suggest that UV-stimulated JNK1 activation promotes UV-induced SCLC apoptosis, while a JNK isoform that is variably activated among the SCLC lines may signal a UV-protective response. 9092556 1997