MAPK8, mitogen-activated protein kinase 8, 5599

N. diseases: 520; N. variants: 4
Disease: Aplasia Cutis Congenita ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita 		0.020 PosttranslationalModification disease BEFREE Treated tumor tissues demonstrated increased rates of apoptosis and JNK activation, with decreased pAkt and H3 phosphorylation, consistent with effects observed in ACC cell lines. 31325906 2019
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita 		0.020 AlteredExpression disease BEFREE More importantly, MIF inhibition could cause the activation of JNK, correlating with the immunohistochemical findings on ACC tissues. 23064787 2013