MAPK8, mitogen-activated protein kinase 8, 5599

N. diseases: 520; N. variants: 4
Disease: Hip Dysplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1328407
Disease: Hip Dysplasia
Hip Dysplasia 		0.010 Biomarker disease BEFREE Normal hip dysplasia and mechanical loosening of tissues showed low expression levels of biomarkers for ER stress (Ca<sup>2+</sup> , JNK, cleaved Caspase-4, IRE1-α, Grp78/Bip, and CHOP), mitochondrion (Bcl-2, Bax, and Cytochrome c), and death receptor (Fas and cleaved Caspase-8) pathways, while osteolytic interface membrane tissues expressed high levels of these biomarkers. 28345781 2017