MYDGF, myeloid derived growth factor, 56005

N. diseases: 295; N. variants: 3
Disease: Ulcerative Colitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 AlteredExpression disease BEFREE In both CD and UC, interleukin (IL)-12 (p40), IL-18, IL-21 and IL-27 transcript levels were higher than in Control. 28533995 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 GeneticVariation disease BEFREE Our data demonstrated that the genetic variant rs153109 in the 5' upstream region of IL-27 is significantly associated with UC in Chinese Han individuals. 28069403 2017
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 Biomarker disease BEFREE The IL-27 was significantly elevated in active UC and CD patients, and it was associated with disease severity. 27221243 2016
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 GeneticVariation disease BEFREE Disease type-stratified subgroup analysis yielded increased risk of related diseases in IL-27 rs181206 T>C carriers in the allele model in immune thrombocytopenia (ITP), asthma, and esophageal cancer (EC) subgroups (ITP: OR=0.69, 95%CI=0.53~0.88, P=0.004; asthma: OR=0.60, 95%CI=0.41~0.89, P=0.010; EC: OR=0.79, 95%CI=0.64~0.97, P=0.026); and IL-27 rs153109 A>G polymorphism was remarkably associated with the increased risk of related diseases in the allele model in ovarian cancer (OC), systemic lupus erythematosus (SLE), tuberculosis (TB), ulcerative colitis (UC), and chronic obstructive pulmonary disease (COPD) subgroups (all P<0.05). 26950245 2016
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 GeneticVariation disease BEFREE IL-27 polymorphisms might play a protective role for the development of UC in the Mexican population. 26905929 2016
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 Biomarker disease BEFREE IL-27 transcripts are significantly elevated in active Crohn's disease (CD) but not in ulcerative colitis (UC). 19686419 2009
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 Biomarker disease BEFREE IL-1beta, IL-6, IL-12, and IL-27 were higher in affected areas compared to unaffected ones in UC but not CD. 19657406 2009
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.080 GeneticVariation disease BEFREE First, direct sequencing of the coding regions of the IL-25 gene in 40 patients with Crohn's disease or ulcerative colitis revealed only a newly reported polymorphism (c424C/A) in exon 2. 14641539 2003