MYDGF, myeloid derived growth factor, 56005

N. diseases: 295; N. variants: 3
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE We found that IL-27 inhibits in vitro tumor growth of human melanomas and greatly enhances the expression of TNF-related apoptosis inducing ligand (TRAIL) in a dose-dependent manner. 24155891 2013
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease BEFREE In this study, we demonstrate that IL-27 also possesses a direct antiproliferative activity on melanoma. 18453571 2008
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE In this study, we further evaluated the antitumor and antiangiogenic activities of IL-27, using poorly immunogenic murine melanoma B16F10 tumors, which were engineered to overexpress single-chain IL-27 (B16F10 + IL-27). 16751375 2006