PDGFC, platelet derived growth factor C, 56034

N. diseases: 69; N. variants: 9
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.030 Biomarker phenotype BEFREE Based on these findings, we suggest that PDGF-Cb might act as a dominant negative molecule regulating the secretion of PDGF-C, and that deregulation of full-length PDGF-C is involved in RCC tumorigenesis. 18588873 2008
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.030 Biomarker phenotype BEFREE Moreover, PDGF-C transgenic mice represent a unique model for the study of hepatic fibrosis progressing to tumorigenesis. 15728360 2005
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.030 Biomarker phenotype BEFREE These results suggest that PDGF-C may be a significant mediator of EWS/FLI driven oncogenesis. 11313995 2001