Disease: Leukemogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis 		0.030 Biomarker disease BEFREE Thus, while MEK1 restricts proliferation and tumorigenesis in some cellular and genetic contexts, it cannot be considered a tumor suppressor in the context of leukemogenesis. 27741509 2016
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis 		0.030 Biomarker disease BEFREE The RAS/mitogen-activated protein kinase (MAPK) pathway molecules (in particular MAPK/ERK kinase 1 (MEK1) and C/EBP transcription factors) include tribbles-binding proteins that are involved in leukemogenesis, and the role of Trib1 as a linker between MAPK signaling and C/EBP degradation is proposed. 21338441 2011
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis 		0.030 Biomarker disease BEFREE Here we report that interaction between Trib1 and MEK1 is required for Trib1-induced leukemogenesis. 20610816 2010