Disease: Adult Medulloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.020 Biomarker disease BEFREE Our study demonstrates the clinical utility of CD271 as both a diagnostic and prognostic tool for SHH medulloblastoma tumors and reveals a novel role for MEK inhibitors in targeting CD271<sup>+</sup> SHH medulloblastoma cells.<b>Significance:</b> This study identifies CD271 as a specific and novel biomarker of SHH-type medulloblastoma and that targeting CD271<sup>+</sup> cells through MEK inhibition represents a novel therapeutic strategy for the treatment of SHH medulloblastoma.<i></i>. 29930101 2018
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.020 Biomarker disease BEFREE Medulloblastoma sensitivity to 17-allylamino-17-demethoxygeldanamycin requires MEK/ERKM. 12709419 2003