|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Prevalence of macroprolactinemia was 21.57% (22/102) in hyperprolactinemia (prolactin >100 ng/ml).
|
30269265 |
2019 |
|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Non-gPRLoma was considered when tumor diameter was ≥ 10 mm and<40 mm associated to hyperprolactinemia (PRL≥200 ng/ml).
|
30396208 |
2018 |
|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to estimate the association between hyperprolactinemia and all-cause and cardiovascular mortality among patients referred for assessment of prolactin.
|
28437810 |
2017 |
|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Prolactin gene polymorphism (-1149 G/T) is associated with hyperprolactinemia in patients with schizophrenia treated with antipsychotics.
|
27776952 |
2017 |
|
Hyperprolactinemia
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Dysregulation of the signaling pathways that govern lactotrope biology contributes to tumorigenesis of prolactin (PRL)-secreting adenomas, or prolactinomas, leading to a state of pathological hyperprolactinemia.
|
25472533 |
2015 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our findings support a possible role of prolactin in emerging psychosis and it could be speculated that stress, which can induce hyperprolactinemia, has a stronger effect on women than on men in emerging psychosis.
|
28214176 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The occurrence of big-big prolactin (PRL) as the major form of circulating immunoactive PRL has been described in ovulatory hyperprolactinemia.
|
3595901 |
1987 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
From a total of 174 people with serum prolactin measurements at study recruitment, 43% (n=74) had HPL, whilst 27% (n=21/78) and 27% (n=26/95) had HPL at 3 and 12months respectively.
|
28755878 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Key aspects include asymptomatic hyperprolactinemia monitoring and fertility considerations with PRL normalisation.
|
28889207 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
CTD_human |
Development of anti-PRL (prolactin) autoantibodies by homologous PRL in rats: a model for macroprolactinemia.
|
17303669 |
2007 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The present study thus suggests that female patients with the A1 allele show greater prolactin response to bromperidol, who may have a high risk for adverse effects associated with neuroleptic-induced hyperprolactinemia.
|
11353448 |
2001 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
LHGDN |
Pituitary production of prolactin and prolactin-suppressing drugs.
|
11721691 |
2001 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
A total of 95% of the 20 patients with hyperprolactinemia had progressive disease (PD), according to CT results, whereas only 2 patients (33%) out of 6 with stable PRL levels had PD (p = 0.004).
|
28407622 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Univariate survival analysis showed that patients with pretherapeutic hyperprolactinemia had a significantly shorter overall survival than patients with pretherapeutic PRL <15.0 ng/mL serum (p =.0009).
|
10748449 |
2000 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
This review aims to summarize current knowledge about PRL and its receptor, role in reproductive axis and presents information of hyperprolactinemia in reproductive medicine.
|
17307904 |
2007 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Although there were significant differences in the prevalence of hyperprolactinemia and metabolic syndrome according to the antipsychotic received, multivariant regression analysis did not show a correlation between sexual dysfunction and prolactin, sexual hormones, type of antipsychotic received, psychotic psychopathology or metabolic syndrome.
|
30552811 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
It was also demonstrated that prolactin played an important role in body weight regulation and hyperprolactinemia can promote appetite and accelerate fat deposition.
|
30124145 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Molecular studies are shedding light on the pathophysiology of hyperprolactinemia and the effects of excess prolactin production on the reproductive system.
|
31045655 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
We aimed to determine if the observed hyperprolactinemia is due to a vascular-derived or known prolactin secretagogue from the injured ICA, analogous to pregnancy-associated hyperprolactinemia putatively due to placental factors.
|
28828544 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
In this review, we provide an update on the diagnostic and management approaches for the patient with hyperprolactinaemia and on the current data looking at the impact of high prolactin on metabolism, cardiovascular and immune systems.
|
31847209 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The odds of hyperprolactinemia in the no/low prolactin elevation cohort were 4-5-times lower than that in the high/moderate prolactin elevation cohort (odds ratio =0.21; p < .001).
|
30188234 |
2018 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Hyperprolactinemia is an inevitable consequence of treatment with antipsychotic agents to some extent because prolactin response to antipsychotics is related to dopamine blockade.
|
18579277 |
2008 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The association of hyperprolactinemia with the severity of the clinical picture has also been demonstrated, higher prolactin values indicating a stronger clinical picture, which calls into question the protective role of prolactin in psychotic disorders.
|
31158115 |
2019 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
Antipsychotics are the most common pharmacological agents which cause hyperprolactinemia The aim of this review is to describe PRL physiology, PRL biological effects and pathway to the diagnosis, causes, consequences of HPRL focusing on the antipsychotic effects on the PRL.
|
28440197 |
2017 |
|
Hyperprolactinemia
|
0.600 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to determine the frequency of hyperprolactinaemia in patients with colorectal cancer before, during, and after surgery, and also to determine whether prolactin is produced by these tumours.
|
10621834 |
1999 |