PRL, prolactin, 5617

N. diseases: 506; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 Biomarker group BEFREE Many studies have provided insight into the complex hypothalamic-pituitary networks controlling prolactin secretion patterns in different species using a range of techniques. 31843563 2020
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 Biomarker group BEFREE Prolactin-Secreting Lung Adenocarcinoma Metastatic to the Pituitary Mimicking a Prolactinoma: A Case Report. 30137505 2019
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE In women with PCOS, PRL levels exceeding 85.2 ng/mL are highly suggestive of a prolactinoma warranting pituitary imaging. 29845629 2018
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE The increased levels of pituitary PRL were observed in both <i>slc12a10.2</i>- and <i>slc12a3</i>-deficient fish. 30515132 2018
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 Biomarker group BEFREE The Pituitary-Thyroid Axis and Prolactin Secretion in Hemodialysis Patients in Two Endemic Regions of Eastern Germany. 29475205 2018
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE We found that, although the expression of pituitary PRL increased steadily during pregnancy, its ovarian receptor (PRLR) reached its maximum in midpregnancy and drastically decreased at term pregnancy. 30013596 2018
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE Leptin Stimulates Prolactin mRNA Expression in the Goldfish Pituitary through a Combination of the PI3K/Akt/mTOR, MKK<sub>3/6</sub>/p<sup>38</sup>MAPK and MEK<sub>1/2</sub>/ERK<sub>1/2</sub> Signalling Pathways. 29261147 2017
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 GeneticVariation group BEFREE The aim of the present study was to construct a co‑expression network of differently expressed genes (DEGs) in prolactin pituitary (PRL) tumor metastasis. 24736764 2014
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 Biomarker group BEFREE Pituitary-derived prolactin (PRL) is a well-known regulator of the lactating mammary gland. 17587388 2007
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE The transcription factor pituitary-1 (Pit-1) is mainly expressed in the pituitary gland, where it has critical roles in cell differentiation and as a transcriptional factor for GH and prolactin (PRL). 16061841 2005
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE PrRP functions as a prolactin-secreting factor through binding with PrRP-R, which is extensively expressed in the human pituitary. 10984631 2000
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 AlteredExpression group BEFREE The transcription factor pituitary-1 (Pit-1) is a homeodomain-containing protein that is expressed mainly in the pituitary, where it drives the expression of growth hormone, prolactin, and thyroid-stimulating hormone beta chain genes. 9828108 1998
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 GeneticVariation group BEFREE Although there was no difference in the levels of PRL-R mRNA in PRL adenomas from men and premenopausal and postmenopausal women, patients treated with bromocriptine before pituitary surgery had significantly lower levels of PRL-R compared to all other groups. 9062514 1997
CUI: C0032002
Disease: Pituitary Diseases
Pituitary Diseases
0.100 Biomarker group BEFREE The diagnosis of a pituitary tumor is made by pituitary imaging and selected hormone assays (mainly PRL). 9167954 1997