|
Depressed mood
|
0.090 |
GeneticVariation
|
phenotype |
BEFREE |
Investigating the potential role of BDNF and PRL genotypes on antidepressant response in depression patients: A prospective inception cohort study in treatment-free patients.
|
31611000 |
2019 |
|
Depressed mood
|
0.090 |
AlteredExpression
|
phenotype |
BEFREE |
76 sexually active men on MMT (mean age = 43.30 ± 10.32 years) and 31 men on BMT (mean age = 41.87 ± 9.76 years) from a Southeast Asian community were evaluated using plasma total testosterone (TT) and prolactin levels, body mass index, social demographics, substance use measures, and depression severity scale.
|
29275046 |
2018 |
|
Depressed mood
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Relevant physiological parameters (plasma prolactin, concentrations of catecholamine metabolites in plasma, and 24-hour urine) and each subject's mental state (Positive and Negative Syndrome Scale, Hamilton Rating Scale for Depression, visual analogue scale, Beck Depression Inventory II) were assessed at the start and end of the trial.
|
29731635 |
2018 |
|
Depressed mood
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
However, the active control performed better than SGA LAIs in relapse to depression, MADRS, and prolactin-related AEs.
|
30417552 |
2018 |
|
Depressed mood
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
Even though its effects during pregnancy and lactation, stress, anxiety, and depression are well studied, recent work on this hormone has brought to light a new role of PRL: that of a protective agent against brain damage and, consequently, against neurodegeneration.
|
29378204 |
2018 |
|
Depressed mood
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
The aim of the present study was to evaluate the roles of depression, stress, and anxiety in LP, as well as serum levels of UA and PRL as potential biomarkers of disease activity and compare these findings with those of the control group.
|
28367894 |
2017 |
|
Depressed mood
|
0.090 |
AlteredExpression
|
phenotype |
BEFREE |
The obtained results indicate that the basal PRL level in rat plasma correlates with a good response to treatment in the animal model of depression.
|
28336340 |
2017 |
|
Depressed mood
|
0.090 |
Biomarker
|
phenotype |
BEFREE |
The hormone prolactin (PRL) plays a crucial role for the initiation and maintenance of maternal behavior, and is also associated with the etiology of mood disorders in women, especially for depression.
|
28359983 |
2017 |
|
Depressed mood
|
0.090 |
AlteredExpression
|
phenotype |
BEFREE |
In human studies, serum OXT and PRL levels have been associated with depression and related phenotypes.
|
20547007 |
2010 |