PRM2, protamine 2, 5620

N. diseases: 9; N. variants: 3
Disease: Oligospermia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028960
Disease: Oligospermia
Oligospermia 		0.030 AlteredExpression disease BEFREE Down-regulation has been found in the protamine 1 and protamine 2 expression levels in the oligospermia group compared to the proved fertile group with fold change (0.001 and 0.0002 respectively). 31762067 2020
CUI: C0028960
Disease: Oligospermia
Oligospermia 		0.030 GeneticVariation disease BEFREE Our data revealed that g.298 G>C transversion in PRM2 was not associated with oligozoospermia (P > 0.05). 27216534 2016
CUI: C0028960
Disease: Oligospermia
Oligospermia 		0.030 Biomarker disease BEFREE Haplotype analysis of PRM1 and PRM2 in combination exhibited that haplotype TACCGGC exhibited a significant protective effect against the occurrence of oligozoospermia when compared with controls (P=0.002, Bonferroni correction, OR 0.602). 23079002 2012