PROP1, PROP paired-like homeobox 1, 5626

N. diseases: 117; N. variants: 30
Disease: Craniopharyngioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010276
Disease: Craniopharyngioma
Craniopharyngioma 		0.030 GeneticVariation disease BEFREE The differentiation between PROP1 mutation associated pituitary enlargements from craniopharyngioma, pituitary adenoma, dys-germinoma, or Rathke's pouch cyst, is critical for the correct patient management. 23831233 2013
CUI: C0010276
Disease: Craniopharyngioma
Craniopharyngioma 		0.030 AlteredExpression disease BEFREE We hypothesized that dysregulated PROP1 expression could also be involved in the pathogenesis of craniopharyngiomas 22086512 2011
CUI: C0010276
Disease: Craniopharyngioma
Craniopharyngioma 		0.030 GeneticVariation disease BEFREE We found no mutations in HESX1, PROP1, and POU1F1 genes and four polymorphisms in PROP1 gene which were in Hardy-Weinberg equilibrium and had similar allelic frequencies in craniopharyngioma and controls. 21761366 2010