PARD3, par-3 family cell polarity regulator, 56288

N. diseases: 68; N. variants: 15
Disease: Squamous cell carcinoma of esophagus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		0.030 AlteredExpression disease BEFREE CONCLUSIONS Overexpression of PARD3 could be a promising new therapeutic intervention against ESCC. 28526815 2017
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		0.030 GeneticVariation disease BEFREE Of the 74 ESCC tumors, 20 (27%), 11 (15%), and 13 (18%) were negative for PAR-3, ZO-1, and claudin-1 proteins, respectively. 28188749 2017
CUI: C0279626
Disease: Squamous cell carcinoma of esophagus
Squamous cell carcinoma of esophagus 		0.030 AlteredExpression disease BEFREE Our results suggest that deletion and reduced expression of PARD3 may be a novel mechanism that drives the progression of ESCC. 19503097 2009