AZGP1, alpha-2-glycoprotein 1, zinc-binding, 563

N. diseases: 101; N. variants: 4
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE These findings demonstrate that ZAG can promote the browning of white adipose tissue and can serve as a potential therapeutic target for treating metabolic diseases such as obesity. 31790716 2020
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE The identified studies show that subjects with obesity have low serum concentrations of zinc and ZAG, as well as low expression of the genes encoding this protein. 30929134 2020
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Zinc-α2-Glycoprotein Is Associated with Obesity in Chinese People and HFD-Induced Obese Mice. 29467670 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE ZAG concentrations were significantly lower in OB compared to NW group (100 ± 34 vs. 106 ± 31 ng/ml; p = 0.007). 29128140 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.080 AlteredExpression disease BEFREE The purpose of this study is to investigate the relationships between adipose tissue ZAG expression and central obesity, and the effects of six-months of weight loss (WL) or aerobic exercise + weight loss (AEX + WL) on ZAG expression. 24929893 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Subcutaneous AT ZAG was reduced in obesity, with a trend to further decrease with prediabetes and type 2 diabetes. 24753506 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.080 GeneticVariation disease BEFREE Our data, for the first time, suggest the genotypes of rs4215 in ZAG gene are significantly associated with obesity in Chinese north Han population. 22425975 2012
CUI: C0028754
Disease: Obesity
Obesity 		0.080 Biomarker disease BEFREE Role of β-adrenergic receptors in the anti-obesity and anti-diabetic effects of zinc-α2-glycoprotien (ZAG). 22227600 2012