RELN, reelin, 5649

N. diseases: 178; N. variants: 52
Disease: Presenile dementia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.310 AlteredExpression disease BEFREE Our findings suggest that up-regulation of reelin may be a compensatory response to tau-related or beta-amyloid stress associated with AD even prior to the onset of dementia. 20452100 2011
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.310 Biomarker disease CTD_human Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice. 20610758 2010